OpenScope Logo

OpenScope Community Predictive Processing

Welcome to the OpenScope Community Predictive Processing repository! This website serves as a hub for community-driven contributions, documentation, and project tracking for our collaborative neuroscience research initiative.


🚀 Quick Start Guide

If you are a... Start here
New Contributor How to Contribute and Collaboration Policy
Experimental Scientist Experimental Plan and Hardware Overview
Data Scientist Analysis Plan and Experiment Summary
Curious Visitor FAQ and Project Overview below

🧠 Scientific Context

This project is described in our paper Neural mechanisms of predictive processing: a collaborative community experiment through the OpenScope program.

Predictive processing theorizes that the brain continuously predicts sensory inputs, refining neuronal responses by minimizing prediction errors. Our collaborative experiments test these mechanisms using mismatch stimuli in mice and primates.

The resulting datasets are shared via the OpenScope program and from collaborating laboratories, fostering community analysis and iterative refinement of predictive processing models.


📋 Experimental & Analysis Framework

📝 Experimental Design

Our experiments investigate neural responses to various prediction violations using carefully designed paradigms.

Experimental Plan →
Detailed Methods →

📊 Analysis Methods

Our analytical approach addresses key questions about information encoding in prediction errors and neural mechanisms.

Analysis Plan →
Experiment Summary →

Methodology

  • Subjects: Experiments conducted on mice and primates to compare mechanisms across species
  • Techniques: In-vivo two-photon imaging and electrophysiological recordings
  • Data Sharing: All datasets collected and shared openly to enable community analysis

Key Resources


👥 Community & Collaboration

This project thrives on community involvement and collaborative research. We welcome contributions from researchers, data analysts, and developers.

How to Contribute

Learn how you can participate in this community science project.

Contribution Guide →

Team & Partners

Meet the researchers and institutions involved in this collaborative project.

Project Team →
  • Collaboration Policy: Guidelines for respectful and productive collaboration
  • FAQ: Answers to frequently asked questions about the project

Thank you for being part of the OpenScope Community Predictive Processing project!